A greasy grip

Development of latent fingerprints on greasy surfaces.

Getting a GRIP (DRAFT)

This paper describes a portable implementation of the Graph Reduction in Parallel (GRIP) software, built on the Parallel Virtual Machine (PVM) process control system. Using this system, it is easy for anyone to “get a GRIP” without needing to invest in special-purpose hardware. An important contribution of this paper is its detailed description of GRIP’s Intelligent Memory Unit (IMU) software.

Autotaxin: inhibiting a greasy pocket Medicinal significance of autotaxin

Autotaxin (ATX) is a secreted glycoprotein that has been implicated in various physiological and pathophysiological processes, including vascular and neural development, lymphocyte trafficking, fibrosis and tumour progression. ATX functions as lysophopholipase D (lysoPLD), hydrolysing lysophosphatidylcholine (LPC) into the signalling lipid lysophosphatidic acid (LPA). LPA stimulates cell migrat...

Mycobacterial Biofilms: A Greasy Way to Hold It Together

Microorganisms growing on surfaces can form biofilms under certain conditions. In this issue of Cell, Ojha et al. (2005) investigate biofilm formation in mycobacteria. They identify new cell-wall components that are required for the formation of architecturally complex mature biofilms in these bacteria and the surprising involvement of a chaperone protein in this process.

Getting a Grip on Complexes

We are witnessing tremendous advances in our understanding of the organization of life. Complete genomes are being deciphered with ever increasing speed and accuracy, thereby setting the stage for addressing the entire gene product repertoire of cells, towards understanding whole biological systems. Advances in bioinformatics and mass spectrometric techniques have revealed the multitude of inte...